Welcome to the National Children’s Study Archive!

The National Children's Study (NCS) Archive is an information, data, and sample repository for the National Children's Study. The goal of the Archive is to share data and samples collected from over 12,000 women, fathers, and children in the National Children's Study from 2009 to 2014 for scientific research, and to make available a wide array of study protocols, procedures, and instruments developed for the National Children's Study.

The National Children's Study, authorized by the U.S. Congress in 2000, under the Children's Health Act, was a planned national cohort study of environmental health effects on 100,000 children; however, the Study was ended in 2014 by the National Institutes of Health before it was fully accrued. The Archive assembles the knowledge and experience gained from the NCS to serve as an ongoing resource to inform future child health and development research.

Participants

The Study collected information on demographics, medical history, health status and behaviors, physical measurements, child development, psychosocial and cognitive assessments, and environmental exposures. These data, currently represented by more than 14,000 variables, are available for continued research. Tools for exploring this data are available to registered users.

A curated teaching dataset is available for use in undergraduate or graduate level biostatistics or public health instruction programs – Teaching Dataset.

Reports and Charts

Biological (blood, urine, saliva, nails, hair, vaginal swab, cord blood, placenta, and breast milk) and environmental (water, air, dust) samples were collected from a subset of families. There are currently over 160,000 biological samples, most with consent for genetic analysis, and more than 3,000 environmental samples available for research analysis.

Blood, urine, nail, hair, swab, umbilical cord, placenta, milk, water, and air samples

These data and samples are freely available, with an approved research request, for scientific research. For study documents and information about available data and samples, please sign up for the registered website.

Log In/Register

Registered Resources

Registered users have access to additional resources to promote and cultivate new ideas for further exploration of existing data and samples. Several sets of de-identified Study visit data are available for researchers to explore, as well as search tools for defining and connecting Study protocol and data elements.

Registered users can propose new research projects using available NCS data. Projects and proposals are tracked and managed with an easy-to-use online system. Researchers with approved projects will be able to analyze NCS data on virtual workstations within a secure Researcher Portal supported by Archive Staff.

Persons with disabilities and others having difficulty accessing information in these documents should e-mail NCSArchive@s-3.net for assistance.

Federal Register Publication of 60-Day Comment Request on NCS Archive Information Collection Renewal

The NCS Archive invites review of our most recent Federal Register notice. To learn more, follow the title link.

Alcohol and Tobacco Prevalence and Cessation in the National Children’s Study

The NCS Archive has an exploratory examination of the Alcohol and Tobacco Prevalence and Cessation before and during Pregnancy. To learn more, follow the title link.

Placental Atlas Tool

NICHD recently launched the Placental Atlas Tool, a website focused on the placenta research community. To learn more, follow the title link.

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