Announcement of NICHD Funding Opportunity (Update)
Posted by Peter Gilbertson on Nov. 27, 2017, 9:29 a.m.
We call your attention to the recent NICHD Program Announcement PA-17-299, “Small Grants for Secondary Analyses of Existing Data Sets and Stored Biospecimens (R03)”, which may be applied to data and samples from the NCS Archive.
This Funding Opportunity Announcement (FOA) encourages applications that propose to conduct secondary analyses of publicly available NICHD-funded data sets or stored biospecimens. The goal of this program is to facilitate innovative yet cost-effective research utilizing data and biospecimens collected with NICHD resources. R03 grants provide up to $50,000 per year in direct costs for a total project period of up to two years.
The Open Date (Earliest Submission Date) is September 16, 2017. Follow this link to learn more - https://grants.nih.gov/grants/guide/pa-files/PA-17-299.html.
Part 2.Section1. Funding Opportunity Description has been updated: Notice of Change in PA-17-299 "Small Grants for Secondary Analyses of Existing Data Sets and Stored Biospecimens (R03)"
The list of initiative supported secondary analyses has been expanded to include NIH and NICHD-supported HIV/AIDS data and specimens.
The full list of concepts is now but is not limited to:
- Physiological factors affecting change (e.g., endocrine, musculoskeletal health, reproductive health, intellectual function, and behaviors) at different points in the life span, including factors contributing to health and healthy development across the life course;
- Determinants, including genetic determinants, of health, human development, disability, and disease in conditions of interest to the NICHD;
- How positive and negative risk factors for health, health behaviors, and healthy development differ by age;
- How positive and negative risk factors differ for health and developmental outcomes differ across stages of disease or condition progression, and/or in the presence or absence of co-existing conditions;
- Early exposures and conditions, including those experienced prenatally and or by prior generations, that influence health, development, or risk of disease and injury in later life, including later in childhood, adolescence, and young adulthood;
- Long-term effects of interventions aimed at addressing conditions related to health, development, disability, or injury, including both the long-term effects on the targeted condition itself and other health-related outcomes;
- Health effects, direct and/or indirect, resulting from exposure to a traumatic event or chronic and persistent exposure to trauma;
- How alternative treatment regimens or health care management strategies influence the effectiveness and safety of treatment;
- How the effects of interventions in clinical trials differ by age, race, gender, disability, or other factors;
- Exploratory analysis, including assays on stored biospecimens, to explore effects of interventions on additional outcomes;
- Analysis and meta-analysis of existing data sets to inform designs of future clinical trials (e.g., to determine prevalence of a disease or condition, or a combination of conditions in a population of interest; to estimate effects size of an intervention and duration of treatment in a population of interest, etc.);
- Analysis or meta-analysis of existing data sets to explore opportunities for and determine the need for comparative effectiveness clinical trials in a topic area;
- Methodology development: Single or multiple data sets may be used to develop and test new analytic approaches for any of the above topics;
- Natural history studies of rare or common disorders or conditions that may inform stratification of cohorts for biomarker discovery or development of treatments or interventions;
- Identifying biomarkers of disease or injury progression, functional impairment, treatment response, and functional recovery;
- Environmental factors that support or challenge health maintenance and/or recovery following injury or illness;
- Analyses defining outcomes related to disability or injury effective at different time points after onset;
- Pharmacokinetics analysis of existing data sets that will help improve pharmacotherapy for neonatal and pediatric populations;
- Genotyping utilizing existing samples to assist in pediatric personalized medicine;
- Genotype-phenotype correlations based on existing data and samples to assist setting up primary outcomes for pediatric clinical trials;
- Analysis of maternal blood or imaging data to establish differences between normal versus pathological placental development and/or function across pregnancy;
- Analysis of NIH and NICHD-supported HIV/AIDS data and specimens to advance scientific knowledge related to HIV pathogenesis, transmission, prevention and cure for infants, children, adolescents, and women of reproductive age (pregnant and non-pregnant).